pylimma.mroast

pylimma.mroast(y, index, design=None, contrast=None, geneid=None, set_statistic='mean', gene_weights=None, var_prior=None, df_prior=None, nrot=1999, approx_zscore=True, legacy=False, adjust_method='BH', midp=True, sort='directional', rng=None, **lmfit_kwargs)

Rotation gene-set test over many sets.

Port of R limma’s mroast.default. See roast() for the single-set API; this version returns a pandas.DataFrame.

The sort argument accepts True/False (aliased to "directional" / "none") as well as the R strings.

Return type:

DataFrame

Parameters:

• set_statistic (str)

• gene_weights (ndarray | None)

• var_prior (float | None)

• df_prior (float | None)

• nrot (int)

• approx_zscore (bool)

• legacy (bool)

• adjust_method (str)

• midp (bool)

• sort (str)